By Jacques Descotes
Lyon-RTH Laennec college of drugs, France. advent to key immunotoxicological matters. Considers the wellbeing and fitness outcomes of immunotoxicity and addresses the cutting-edge equipment used to discover and review unforeseen immunotoxic results of xenobiotics, either preclinically and clinically. For undergraduate and graduate scholars. Hardcover, softcover additionally to be had.
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Extra info for An introduction to immunotoxicology
Et al. (1980) Fatal disseminated BCG infection in an 18–year-old boy. Lancet, ii, 1332–1334. B. F. (1991) Environmental effects on the human immune system and the risk of cancer: facts and fears in the era of AIDS. Environ. Carcino. Ecotox. , 9, 155–206. NICHOLSON, V. C. (1994) Infectious complications in solid organ transplant recipients. Surg. Clin. N. , 74, 1223–1244. PENN, I. (1994) Malignancies. Surg. Clin. N. , 74, 1247–1257. S. R. (1991) AIDS, drugs of abuse and the immune system: a complex immunotoxicological network.
Interestingly, such adverse reactions have been noted with immunostimulating substances which can activate macrophages, either directly (such as microbial extracts) or via the release of interferon-␥, which in turn results in the release TNF-␣ and IL-1. , 1995). , 1991). Exacerbation of underlying diseases Shortly after their introduction into the clinical setting, immunostimulating agents were found to exacerbate or facilitate a variety of underlying diseases in treated patients, namely dormant diseases, autoimmune diseases and immuno-allergic reactions.
In vivo augmentation of nonspecific and specific immune responses. Clin. Immunol. , 26, 10–17. D. (1990) Drug interactions involving immunologic agents. Part I. Vaccinevaccine, vaccine-immunoglobulin, and vaccine drug interactions. DICP, Ann. , 24, 67–81. W. R. (1983) Depression of theophylline elimination following BCG vaccination. Br. J. Clin. , 16, 735–737. , et al. (1989) Effects of interferon-a on theophylline pharmacokinetics and metabolism. Br. J. Clin. , 27, 795–802. KOREN, G. and GREENWALD, M.